Sarcomas are malignant (cancerous) tumors that arise from cells that make up the connective tissues, which can be broadly broken down into bone, visceral, and soft tissue. Soft tissue sarcomas account for ∼1% of adult solid tumors. Many are highly aggressive.
Soft tissue tumors represent a heterogeneous and complex group of mesenchymal lesions that may show a broad range of differentiation. Histologic classification is based according to the normal mesenchymal tissue it most resembles with over 50 types that differ in pathologic and clinical features.
The therapeutic management of those with soft tissue sarcoma requires the coordinated efforts of a multidisciplinary and multiprofessional care team of medical professionals, such as oncologists, radiation oncologists, pathologists, oncology or orthopedic surgeons, oncology nurses, psychiatrists, nutritionists, and other healthcare specialists. Psychosocial support for the entire family is also essential.